The adaptor molecule RIAM integrates signaling events critical for integrin-mediated control of immune function and cancer progression
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منابع مشابه
The adaptor molecule RIAM integrates signaling events critical for integrin-mediated control of immune function and cancer progression.
Lymphocyte activation requires adhesion to antigen-presenting cells. This is a critical event linking innate and adaptive immunity. Lymphocyte adhesion is accomplished through LFA-1, which must be activated by a process referred to as inside-out integrin signaling. Among the few signaling molecules that have been implicated in inside-out integrin activation in hematopoietic cells are the small ...
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ژورنال
عنوان ژورنال: Science Signaling
سال: 2017
ISSN: 1945-0877,1937-9145
DOI: 10.1126/scisignal.aam8298